Nobuaki Kobayashi Selected Research

Poly G

1/2020	Class A CpG oligodeoxynucleotide inhibits IFN-γ-induced signaling and apoptosis in lung cancer.
2/2013	Oligodeoxynucleotides expressing polyguanosine motifs promote antitumor activity through the upregulation of IL-2.

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Nobuaki Kobayashi Research Topics

Disease

31	Heart Failure 01/2022 - 02/2009
17	Neoplasms (Cancer) 01/2022 - 01/2003
14	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 04/2006
9	Acute Coronary Syndrome 01/2018 - 10/2009
9	Thrombosis (Thrombus) 10/2016 - 10/2010
8	Lung Neoplasms (Lung Cancer) 05/2021 - 10/2019
7	Acute Kidney Injury (Acute Renal Failure) 06/2019 - 01/2014
6	Tuberculosis (Tuberculoses) 03/2021 - 01/2005
6	Rupture 01/2019 - 10/2009
5	Myocardial Infarction 01/2017 - 01/2006
5	Hepatocellular Carcinoma (Hepatoma) 08/2009 - 09/2002
4	Cardiovascular Diseases (Cardiovascular Disease) 10/2021 - 12/2008
4	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2021 - 06/2019
4	ST Elevation Myocardial Infarction 10/2016 - 01/2011
4	Cholangiocarcinoma 11/2009 - 01/2003
3	Adenocarcinoma 03/2022 - 08/2007
3	Neoplasm Metastasis (Metastasis) 01/2022 - 12/2006
3	Vascular Diseases (Vascular Disease) 01/2022 - 06/2019
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2021 - 01/2016
3	Death (Near-Death Experience) 01/2021 - 01/2010
3	Cardiac Sudden Death (Sudden Cardiac Arrest) 12/2020 - 01/2013
3	Hyperplasia 03/2016 - 11/2014
3	Pathologic Constriction (Stenosis) 07/2013 - 06/2002
2	COVID-19 01/2022 - 01/2021
2	Idiopathic Pulmonary Fibrosis 01/2022 - 10/2020
2	Dyspnea (Shortness of Breath) 01/2022 - 03/2020
2	Malnutrition (Nutritional Deficiencies) 01/2021 - 01/2020
2	Infections 12/2020 - 11/2009
2	Pneumonia (Pneumonitis) 10/2020 - 12/2009
2	Hyperuricemia 10/2020 - 09/2020
2	Sclerosing Cholangitis 07/2020 - 01/2003
2	Pulmonary Tuberculosis 09/2019 - 01/2017
2	Atherosclerosis 12/2018 - 04/2017
2	Diabetes Mellitus 09/2018 - 10/2016
2	Chronic Renal Insufficiency 10/2017 - 11/2016
2	Respiratory Insufficiency (Respiratory Failure) 03/2014 - 01/2005
2	Aortic Dissection 03/2014 - 05/2013
2	Heart Arrest (Cardiac Arrest) 01/2014 - 01/2013
2	Atherosclerotic Plaque (Atheroma) 10/2013 - 01/2012
2	Disease Progression 01/2013 - 06/2004

Drug/Important Bio-Agent (IBA)

14	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2002
6	Uric Acid (Urate)IBA 06/2019 - 11/2016
5	Fatty Acid-Binding ProteinsIBA 11/2021 - 01/2011
5	Pharmaceutical PreparationsIBA 10/2021 - 12/2006
5	CreatinineIBA 01/2020 - 01/2018
5	oxidized low density lipoproteinIBA 10/2013 - 10/2009
5	Proteins (Proteins, Gene)FDA Link 10/2012 - 09/2002
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 02/2009
4	B7-H1 AntigenIBA 01/2022 - 10/2020
4	Tumor Biomarkers (Tumor Markers)IBA 05/2021 - 01/2003
4	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2020
4	BilirubinIBA 01/2021 - 04/2009
4	Xanthine DehydrogenaseIBA 01/2021 - 04/2019
4	LectinsIBA 10/2013 - 10/2009
4	Troponin T (Troponin T1)IBA 05/2013 - 10/2009
3	PlatinumIBA 03/2022 - 10/2019
3	pembrolizumabIBA 03/2022 - 07/2020
3	CollagenIBA 01/2022 - 06/2019
3	AntigensIBA 01/2021 - 11/2005
3	CalciumIBA 12/2020 - 02/2009
3	AlbuminsIBA 12/2020 - 10/2012
3	C-Reactive ProteinIBA 10/2013 - 10/2008
3	Trinitrotoluene (TNT)IBA 10/2013 - 01/2011
3	Sirolimus (Rapamycin)FDA Link 06/2011 - 11/2007
2	Peptides (Polypeptides)IBA 01/2022 - 09/2019
2	Heme Oxygenase-1IBA 01/2022 - 11/2020
2	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2021 - 01/2021
2	Carboplatin (JM8)FDA LinkGeneric 12/2021 - 10/2021
2	Fatty Acid Binding Protein 3IBA 11/2021 - 01/2011
2	Triiodothyronine (Liothyronine)FDA LinkGeneric 10/2021 - 01/2020
2	Paclitaxel (Taxol)FDA LinkGeneric 10/2021 - 11/2014
2	amrubicinIBA 05/2021 - 01/2016
2	PhytohemagglutininsIBA 01/2021 - 12/2020
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2020
2	InterferonsIBA 01/2021 - 04/2009
2	osimertinibIBA 01/2021 - 01/2020
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 09/2020 - 11/2016
2	Poly GIBA 01/2020 - 02/2013
2	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2020
2	CytokinesIBA 01/2020 - 10/2008
2	Nicorandil (SG 75)IBA 12/2018 - 11/2010
2	MB Form Creatine KinaseIBA 01/2016 - 01/2011
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2016 - 01/2011
2	MetalsIBA 11/2014 - 06/2011
2	Glucose (Dextrose)FDA LinkGeneric 03/2013 - 10/2012
2	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)IBA 01/2011 - 10/2009
2	Anti-Bacterial Agents (Antibiotics)IBA 02/2010 - 11/2006
2	Fluorouracil (Carac)FDA LinkGeneric 11/2009 - 02/2009

Therapy/Procedure

14	Stents 10/2016 - 06/2002
11	Therapeutics 01/2022 - 01/2005
11	Critical Care (Surgical Intensive Care) 11/2021 - 10/2008
10	Drug Therapy (Chemotherapy) 03/2022 - 11/2009
3	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 03/2020 - 01/2005
3	Radiotherapy 11/2019 - 11/2009
3	Thrombectomy 01/2019 - 05/2015
3	Percutaneous Coronary Intervention 01/2017 - 12/2008
3	Drug-Eluting Stents 02/2012 - 10/2010
2	Immunotherapy 01/2020 - 02/2013
2	Cardiopulmonary Resuscitation (CPR) 01/2014 - 01/2013
2	Induced Hypothermia 01/2014 - 01/2013